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How Ultrapure Water Can Be Used in Pharmaceuticals For Improved Healthcare

How Ultrapure Water Can Be Used in Pharmaceuticals For Improved Healthcare

25 February 2026

Toby Patrick

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Ultrapure Water (UPW) is a very important part of the pharmaceutical industry, as it has such a high purity level of around 18.2 MΩ cm resistivity, which is perfect for removing ions, organic matter, bacteria and particulate matter. All of this can reduce the quality of medication and turn it into something that can be potentially catastrophic to patients' health.


Hand holding assorted colorful pills on a bright blue background, creating a vibrant and health-focused visual.

It’s mainly used for drug manufacturing, as it can sanitise materials and equipment so everything is kept clean and away from any danger. This improves healthcare and makes it safer for patients by reducing contamination risks. It also improves the stability of therapeutic products for patients who need them to function properly.


This guide will explore how ultrapure water is used in pharmaceuticals and why it’s essential for keeping patients protected while improving their healthcare. Continue reading to learn more.


How Pharmaceutical Industries Improve Healthcare

Safety of Injectables

UPW is used to produce water for injection, the required solvent for injectable medications like vaccines for infectious diseases. These types of medications are used across the world, so it’s crucial that they’re made to be safe to use since they get injected into  the skin and blood flow of patients. This ensures that they are free from endotoxins, microbes and chemical impurities that could cause sepsis or fatal adverse reactions. 


Product Efficacy and Stability

When UPW is used, it can remove ionic and organic contaminants as it prevents chemical interactions that could degrade Active Pharmaceutical Ingredients (APIs). This ensures medications remain stable and effective throughout their existence to prevent wasted medication, all while ensuring patient treatment is always safe to administer.


Preventing Contamination

Small contaminants are dangerous for medications, as they can interfere with how cells grow or cause a patient's body to have a bad reaction. Those within the industry can use UPW to help scientists make sure the environment stays clean and steady so that nothing ruins the medicine. This step is crucial for keeping the treatment safe and making sure it works exactly the way it should for the person taking it.


Sterilisation of Medical Devices

The integration of UPW in the pharmaceutical industry helps to generate clean steam for autoclaving. This ensures that surgical instruments and complex medical equipment are stripped of microscopic bio-burden without the risk of chemical residue. This minimises the transmission of pathogens and significantly reduces hospital infections that can occur from using products that have been contaminated. You can improve the integrity of the medical tools and the lives of the patients they serve.


Accurate Diagnostics

When new medicines are created and tested, scientists must use UPW to ensure their experiments are perfect in order for them to function as intended. This water is so clean that it has been stripped of every impurity that could interfere with testing equipment, making sure that the whole process is carefully constructed. When researchers prepare liquid samples for analysis, even the smallest change can create fake results called ghost peaks on their digital charts. This can ruin the final product of medication, leading to adverse effects on patients.


Formulation of Sensitive Topical Products

When companies make sensitive products like face creams or eye drops, they must use UPW to ensure it’s as safe as possible. Regular water contains tiny minerals and invisible bacteria that can easily irritate your skin or cause painful infections in your eyes. Manufacturers can remove those hidden impurities so the final product is gentle and effective. This high standard of purity protects your health and helps the medicine work exactly as it should without any nasty side effects.


What Technology is Used for UPW?

Continuous Electrodeionization (CEDI)

CEDI is the leading technology for UPW production. Used by water management companies like Xylem, it can replace chemical-based ion exchange with an electrochemical process. This can help to remove any impurities, including carbon dioxide, that can ruin medication. CEDI is a continuous, low-energy-consuming process and avoids the need for chemical regenerants, perfect for cost savings.


Ultraviolet (UV)

UV light can disrupt the DNA of microorganisms to prevent them from growing any bigger, while specific UV wavelengths can break down trace organisms. It helps manufacturers get more protection when making medication, as the water can stay at a consistent quality that will support regulatory compliance.


The pharmaceutical industry couldn’t survive without UPW. It’s the necessary component needed to ensure that all medication is safe to use, as it helps to sterilise machinery used by manufacturers and prevent any contamination from occurring. Without UPW, patients will receive inadequate care, as the medication they take could harm them or give them adverse effects. It’s crucial that companies within the industry keep their patients safe at all times to avoid any legal action from being taken against them.


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The End of the Safety Net: Why Slashing Farm Subsidies Could Threaten the UK’s Food Future

  • Writer: Paul Francis
    Paul Francis
  • Apr 16, 2025
  • 4 min read

Not only do UK farmers now face the looming threat of inheritance tax reforms that could force centuries-old family farms to be sold off - but they’re also contending with a policy shift that dismantles the very foundation of their economic stability: the withdrawal of direct farm subsidies.


A black-and-white cow grazes on a lush, green field with a dense forest in the background. The scene is peaceful and natural.

In a time of global instability - wars in Europe and the Middle East, disrupted trade routes, volatile commodity markets - the UK government is removing financial safeguards that have underpinned British agriculture for decades. And it’s doing so faster than many in the industry can adapt.


The Basic Payment Scheme (BPS), a direct subsidy paid to farmers under the EU’s Common Agricultural Policy (CAP), is in its final years. By 2027, it will be completely gone. In its place: a complex, tiered system of environmental schemes under the umbrella of the Environmental Land Management Schemes (ELMS). Worthy in theory, but in practice? A mess of bureaucracy, delays, and shortfalls.


And the timing couldn’t be worse.


A Lifeline Cut-Off Before the Bridge Was Built

The BPS wasn’t perfect, but it provided one essential function - it kept farms afloat. Payments were calculated based on the amount of land farmed, offering predictability and a cashflow buffer that allowed British farms to invest in new equipment, manage seasonal fluctuations, and ride out the weather, both literal and economic.


Now, payments have been rapidly reduced. By 2024, many farmers had already lost 35%–50% of their BPS income. In 2025, a new cap of £7,200 per farm will apply. That’s a fraction of the £20,000 to £50,000 mid-size farms previously received.


The replacement - ELMS - promises payments for "public goods": improving soil health, reducing carbon emissions, boosting biodiversity. Laudable aims. But ask most farmers, and they’ll tell you: they don’t object to sustainability. What they object to is the speed and scale of the transition, and the fact that the new payments often don’t come close to replacing what’s being lost.


Environmental Schemes: Aspirations Without Infrastructure

At the core of ELMS are three tiers:

  1. Sustainable Farming Incentive (SFI): Encourages low-level changes such as herbal leys, no-till farming, and reducing fertiliser use.

  2. Local Nature Recovery: Pays for habitat restoration and targeted environmental actions.

  3. Landscape Recovery: Funds large-scale, long-term ecosystem restoration, often in collaboration with multiple landowners.


But uptake has been patchy at best. As of late 2024, fewer than half of eligible farms had enrolled in any ELMS scheme. Why?

  • The schemes are confusing. Farmers must navigate different options, overlapping rules, and constant revisions.

  • The application process is time-consuming and opaque.

  • Payments under SFI are often insufficient, especially for mixed or livestock farms in upland areas where land-use change is more difficult.

  • Crucially, many tenanted farmers - nearly a third of all farms in England - face legal and logistical barriers to taking part.


DEFRA has promised streamlining. But meanwhile, farmers are left in limbo - without clear income streams, but still expected to feed the nation.


The Cost of Poor Policy Timing

Agricultural experts, rural economists, and even major retailers have raised alarm bells. In a scathing 2023 report, the National Audit Office warned that DEFRA had failed to communicate the changes effectively, leaving many in the dark about what the new schemes offer.


The NFU (National Farmers’ Union) has repeatedly called on the government to pause BPS cuts until ELMS is fully functioning, but those calls have largely been ignored. In late 2024, a coalition of MPs from all parties demanded a review, warning that this abrupt withdrawal of support could lead to an exodus from the industry.


And that’s not just a theoretical risk. A nationwide NFU survey found that 11% of farmers were considering leaving farming altogether due to the combined impact of reduced subsidies, labour shortages, and rising costs.


Food Security in an Uncertain World

This isn’t just a farming problem - it’s a national one.


The UK is already heavily reliant on imports for key food items. And with international trade routes threatened by conflict in Ukraine, instability in the Middle East, and shipping disruptions in the Red Sea, supply chains are becoming more fragile by the month.


Should we really be cutting back our domestic food production capacity now?


Government ambitions to rewild 10% of farmland, promote biodiversity, and shift toward carbon sequestration may look good on a whiteboard in Whitehall. But on the ground, it’s leading to reduced livestock numbers, lower domestic output, and a growing dependence on foreign markets that may not be as reliable as once assumed.


A Dangerous Gamble

To many farmers, this feels like an ideological experiment being conducted in real-time -with their livelihoods and our food supply on the line. And as supermarket CEOs and farming groups increasingly speak out, it’s clear this isn’t just grumbling from the shires. It’s a cry of alarm from the foundation of the UK’s food system.


Environmental ambition is important. Climate change is real. But so is hunger.

We can pursue sustainability - but not by pulling the rug out from under those who feed us. The government’s subsidy reform may have noble aims, but its execution is flawed, its timeline reckless, and its consequences potentially devastating.


If we want a resilient, secure food future, we must support the people who make it possible - not push them to the brink.

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